المستويات المصلية للتروبونين القلبي T عالي الحساسية (hs-cTnT)‎ لدى مرضى الداء الرئوي المسد المزمن

الملخص EN

Cardiovascular disease CVD is common in patients with Chronic Obstructive Pulmonary Disease (COPD).

High-sensitivity cardiac troponin T (hs-cTnT) in serum indicate cardiac damage.

This study aimed to assess the levels of hs-cTnT in COPD patients without any diagnosed cardiac diseases, either in stable or exacerbation, and its association with patient age and smoking.

In a prospective cross-sectional study composed of 56 COPD patients and 25 normal controls, COPD patients were divided into 2 groups : 26 patient with exacerbation and 30 patient with stable COPD.

Serum hs-cTnT was measured by electrochemiluminescence immunoassay (ECLIA) using Elecsys 2010 Concentration of hs-cTnT were significantly higher in patient group with COPD, as compared to normal control group, but there was no significant difference in the hs-cTnT concentrations between stable and exacerbation COPD patients.

There was no association between serum hs cTnT levels and patient age and smoking.

Our results show elevation in hs-cTnT in COPD patients that indicate undiagnosed injury in the cardiac muscle.

That suggests the role of hs-cTnT in early screening of heart disease in COPD patients in an age independent manner.