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The effects of javanese turmeric (Curcuma xanthorriza Roxb) on fibroblasts, granulation, blood vessel density, and contraction in wound healing of STZ-induced diabetic rats
المؤلفون المشاركون
Kristianto, Heri
Khotimah, Husnul
Sholeha, Ryharti A.
Mardianto, Eky W.
Sani, Hasnah C.
Paratiwi, Hardika A.
المصدر
العدد
المجلد 50، العدد 1 A (31 يناير/كانون الثاني 2023)، ص ص. 1-14، 14ص.
الناشر
جامعة الكويت مجلس النشر العلمي
تاريخ النشر
2023-01-31
دولة النشر
الكويت
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Diabetic ulcers usually occur in the lower extremities of diabetic patients.
One in 20 diabetic patients will develop an ulcer, and 10% of those cases lead to amputation.
This study aimed to investigate the effects of Javanese turmeric (Curcuma xanthorriza) extract on the number of fibroblasts, granulation, blood vessel and the rate of wound contraction in a Wistar rat model of the diabetic ulcer.
This was an experimental study with post-test observations only and randomized control group design.
Rats were divided into five groups: (1) negative control; (2) positive control; (3) P1; (4) P2; and (5) P3.
Every rat was assessed for fibroblast number, granulation, blood vessel density, and wound contraction percentage.
Javanese turmeric extract had a significant effect on histological parameters (fibroblast, blood vessels and tissue granulation) (p < 0.05) and wound contraction (p < 0.05).
The double linear test revealed a significant relationship between fibroblasts, granulation, blood vessel quantity, and wound contraction (p < 0.05).
Correlation and regression tests showed that Javanese turmeric extract explained 91% of the effects on fibroblasts, blood vessels, and granulation.
Treatment with Javanese turmeric extract increased the number of fibroblasts, tissue granulation, blood vessel density and wound contraction in male diabetic wistar rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kristianto, Heri& Khotimah, Husnul& Sholeha, Ryharti A.& Mardianto, Eky W.& Sani, Hasnah C.& Paratiwi, Hardika A.. 2023. The effects of javanese turmeric (Curcuma xanthorriza Roxb) on fibroblasts, granulation, blood vessel density, and contraction in wound healing of STZ-induced diabetic rats. Kuwait Journal of Science،Vol. 50, no. 1 A, pp.1-14.
https://search.emarefa.net/detail/BIM-1499990
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kristianto, Heri…[et al.]. The effects of javanese turmeric (Curcuma xanthorriza Roxb) on fibroblasts, granulation, blood vessel density, and contraction in wound healing of STZ-induced diabetic rats. Kuwait Journal of Science Vol. 50, no. 1 A (Jan. 2023), pp.1-14.
https://search.emarefa.net/detail/BIM-1499990
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kristianto, Heri& Khotimah, Husnul& Sholeha, Ryharti A.& Mardianto, Eky W.& Sani, Hasnah C.& Paratiwi, Hardika A.. The effects of javanese turmeric (Curcuma xanthorriza Roxb) on fibroblasts, granulation, blood vessel density, and contraction in wound healing of STZ-induced diabetic rats. Kuwait Journal of Science. 2023. Vol. 50, no. 1 A, pp.1-14.
https://search.emarefa.net/detail/BIM-1499990
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 10-14
رقم السجل
BIM-1499990
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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