Neurological manifestations observed in infants with megaloblastic anemia

الملخص AR

Two cases of megaloblastic anemia presenting in infancy are described.

Both cases presented with hepatomegaly and developmental delay.

CT scan of the brain showed severe frontal and frontoparietal cranial atrophy, more prominent in an 11-month-old girl born to a mother with dietary deficiency.

This infant died in spite of vitamin B12 supplementation.

The second case, an 8-month-old boy who was being breast-fed, showed mild improvement with vitamin B12 supplementation.