Thyrotoxicosis in Qatar

الملخص AR

A retrospective study of 179 patients with thyrotoxicosis was undertaken to determine the cause of thy¬rotoxicosis in our hospital and the outcome of the three available treatment modalities for patients with hyperthyroid Graves' disease.

Graves' disease was found in 84% of the patients, toxic multinodular goiter in 8.5%, toxic adenoma in 4%, and thyroiditis in 3.5%.

Graves' disease affected women predominantly; the female to male ratio was 3:2, with mean age of 3d±U years.

Ophthalmopathy was seen in 41% of the patients; goiter was absent in 8%.

Most of the patients received antithyroid drugs as primary treatment.

Forty-six patients with Graves' disease were seen in 1989; 89% had antithyroid drugs as primary treatment for a duration of l±0.7 years, 68% relapsed.

Of these relapsed patients, 82% were treated with radioiodine and 11% were treated with surgery.

In 105 patients with Graves' disease treated with radioiodine, 60% were cured; additional doses were needed in 19%; and hypothyroidism developed in 49%.

In 19 patients treated with surgery, 63% were cured; hypothyroidism developed in 16%; and permanent hypocalcemia developed in 5%.

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