The prevalence of metabolic syndrome in coronary artery disease and the association of metabolic syndrome with severity of coronary artery disease

الملخص EN

Metabolic syndrome (MetS) is the major and a common risk factor of many major diseases like Atherosclerotic cardiovascular disease (ASCVD), Cerebrovascular Accidents(CVA) and Diabetes Mellitus.

This study was conducted to assess the association of metabolic syndrome with the Coronary Artery Disease and the severity of CAD evident angiographically.

CAD are the leading causes of Death worldwide.

Materials and Methods In our study 607 patients from both sex was included who presented to the cardiology department suffering from features of ischemic heart disease then underwent coronary angiography and have confirmed CAD with single or multi-vessels diseases, they were aged from 25 to 85 years.

Metabolic Syndrome was defined based on International Diabetes Federation (IDF) criteria(13) as follows: Central obesity (waist circumference: Male > 90 cm, female>80cm) plus any two: Raised triglycerides(>150mg/dl), reduced HDL cholesterol (<40mg/dl in men or <50mg/dl), ), raised blood pressure (systolic ≥ 130 mmHg or diastolic ≥ 85 mmHg or on treatment), or raised fasting plasma glucose (fasting plasma glucose ≥ 100 mg/dl or on treatment).

The results: Among the 607 participants in the study 334(55.02%) were males and 273(44.97%) were females, the mean age of the participant was 57yrs with no significant difference between those who have and haven`t metabolic syndrome.

371(61.1%) patients have metabolic syndrome; females were significantly affected with metabolic syndrome 224(60.4%) than males 147(39.6%) with P value <0.001.

224(82%) of participant females were fulfilling the criteria of metabolic syndrome which is very significantly higher than participant males 147 (44%).

Conclusion: There are high incidences of metabolic syndrome found in CAD, metabolic syndrome MetS is more common in females and its associated with severe CAD.

Preventive measures should be applied at the level of the community for better life styles especially for women.