Pefloxacin in the treatment of childhood nephritic syndrome : a case report
المؤلفون المشاركون
Djoneidi, Maziar
Diallo, Saidou
Bao, Umar
Diop, Therese Moreira
Diouf, Boucar
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 7، العدد 1 (28 فبراير/شباط 1996)، ص ص. 31-33، 3ص.
الناشر
تاريخ النشر
1996-02-28
دولة النشر
السعودية
عدد الصفحات
3
التخصصات الرئيسية
الموضوعات
الملخص EN
The idiopathic nephrotic syndrome (INS) of childhood is characterized chiefly by a remitting and relapsing course and its striking susceptibility to corticosteroid therapy.
We report a case of relapsing nephrotic syndrome associated with urinary tract infection (UTI) treated with pefloxacin, which is a fluoro-quinolone derivative, in a dose of 800 mg per day.
Steroids were avoided because of associated UTI.
The UTI responded well and proteinuria disappeared after ten days of treatment with pefloxacin.
However, the patient developed arthralgia involving the ankles, the knees and the neck.
At this juncture, the drug was discontinued resulting in complete cessation of the joint pain.
Pefloxacin increases the production of interleukin-2, a cytokine whose metabolism is modified during nephrotic syndrome.
It has been used earlier in children with INS with equivocal results.
The toxicity of quinolones for the joints seems more frequent in children, whose cartilage is immature and several cases have been reported.
Studies on a larger number of patients are required before drawing any firm conclusions on the usefulness of pefloxacin in the treatment of INS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Diouf, Boucar& Djoneidi, Maziar& Diallo, Saidou& Diop, Therese Moreira& Bao, Umar. 1996. Pefloxacin in the treatment of childhood nephritic syndrome : a case report. Saudi Journal of Kidney Diseases and Transplantation،Vol. 7, no. 1, pp.31-33.
https://search.emarefa.net/detail/BIM-165580
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Diouf, Boucar…[et al.]. Pefloxacin in the treatment of childhood nephritic syndrome : a case report. Saudi Journal of Kidney Diseases and Transplantation Vol. 7, no.1 (December 1996), pp.31-33.
https://search.emarefa.net/detail/BIM-165580
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Diouf, Boucar& Djoneidi, Maziar& Diallo, Saidou& Diop, Therese Moreira& Bao, Umar. Pefloxacin in the treatment of childhood nephritic syndrome : a case report. Saudi Journal of Kidney Diseases and Transplantation. 1996. Vol. 7, no. 1, pp.31-33.
https://search.emarefa.net/detail/BIM-165580
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 33
رقم السجل
BIM-165580
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر