Intrarenal hemodynamic changes in type 2 diabetic patients

الملخص EN

Back ground : A frequent and early manifestation of diabetic nephropathy is hyaline arteriolosclerosis, characterized by hyaline deposition in the arterioles.

Measurement of the resistive index (RI) by Doppler sonography may be used as a noninvasive method for estimating the severity of arteriolosclerosis instead of invasive renal biopsy Objectives : To study the effect of type 2 DM on intrarenal hemodynamics. Methods : Nineteen patients with type 2 diabetes were included in this study (10 males, 9 females) aged 44 ± 10 years, mean duration of DM was 7 ± 5 years.

The resistive index (RI) of interlobular renal arteries was used to assess the intrarenal hemodynamic changes in diabetic patients and compared to that of the normal subjects Results : Statistically there was significant intrarenal hemodynamic changes in type 2 diabetic patients compared to normal subjects as reflected by higher values of RI in the former.

Also there was significant effect of the duration of DM on intrarenal hemodynamics. Conclusions : Type 2 diabetic patients have higher values of RI compared to nondiabetics, and this increment is proportional to the duration of DM.