Vitamin b6 intake and b6 vitamin concentrations and excretion in blood and urine of cigarette smokers, water-pipe smokers and non smokers

الملخص EN

The aim of this study was to evaluate vitamin B6 and B6 vitamer concentrations [ pyridoxal phosphate (PLP) in plasma and red blood cells and urinary excretion of 4-pyridoxic acid (4-PA)] among adult Saudi cigarettes smokers (n = 85), water pipe smokers (n = 82) and non-smokers (n = 90).

The study also investigated dietary intake of vitamin B6, protein, B6 : protein ratio and % of dietary vitamin B6 from animal sources.

Other biochemical parameters that affect vitamin B6 status including plasma albumin concentration and plasma alkaline phosphatase activity were also determined.

Mean dietary intakes of vitamin B6 for cigarettes smokers group (n = 85), water pipe smokers group (n = 82) and non-smokers group (n = 90) were 2.13 ± 0.72, 2.47±0.77 and 2.09 ± 0.69 mg / day, respectively.

Mean plasma PLP concentrations for the three groups were 26.2 ± 3.2, 44.7±5.1 and 35.0 ± 2.1 nmol / L, respectively.

Mean urinary 4-PA excretions for the three groups were 3.8 ± 1.8, 7.2 ± 3.6 and 4.8±2.2 μmol / day, respectively.

Dietary and biochemical indices indicated an adequate status of vitamin B6.

However, water pipe smokers had significantly higher means of vitamin B6 intake and plasma PLP concentration as well as urinary 4-PA excretion compared to the other two groups.

Bioavailability of dietary vitamin B6 was less in water pipe smokers group compared to the other two groups as determined by % of the vitamin from animal source.

Cigarettes smokers group had significantly lower mean plasma PLP concentration compared to non-smokers groups.

Results of this study suggested that water pipe smoking had no effect on vitamin B6 indices in blood and urine as effect of cigarettes smoking.

Water in the water pipe smoking system may trap chemical components that are generated from tobacco smoking and affect vitamin B6 vitamins in blood and urine.

Further investigations are needed to evaluate influence of water pipe smoking on vitamin B6 indices, with fixed vitamin B6 intake.