![](/images/graphics-bg.png)
Evaluation of the immune response to hepatitis b vaccine in different age groups of the population of sana’a-Yemen
العناوين الأخرى
تقييم الاستجابة المناعية للقاح الالتهاب الكبدي ب على مختلف المجموعات العمرية من السكان لمدينة صنعاء ، اليمن
المؤلفون المشاركون
al-Shamahi, Hasan Abd al-Wahhab
al-Moyed, Tageia Abd al-Karim
al-Medhagi, Anwar G.
المصدر
Journal of the Bahrain Medical Society
العدد
المجلد 21، العدد 1 (31 مارس/آذار 2009)، ص ص. 201-206، 6ص.
الناشر
تاريخ النشر
2009-03-31
دولة النشر
البحرين
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Objectives : The study was made to evaluate the immune response to HBV among individuals with different ages and sexes by measuring the level of circulating anti-HBs antibodies over an interval of 1 to 5 years after immunization with the three doses of hepatitis B vaccine.
Methods : A total of 300 individuals vaccinated against HBV prior to the study were included, of whom males represent 47.7 % and females 52.3 % with a mean age of 26.67 years.
Sera were tested for HBsAg and anti-HBc by qualitative ELISA and anti-HBs by ELISA quantitative technique.
The individual’s data were collected in a pre-designed questionnaire including : vaccination date, number of doses of vaccine, sex, occupation and age at the time of the present study.
Results : Two hundred and sixteen (81.2 %) of 266 individuals (lacking both HBsAg and anti-HBc) responded to the vaccine with anti-HBs antibody level ≥10 mIU / ml.
Thirty-four (11.3 %) of 300 individuals were reactive to anti-HBc, indicating an immune response due to previous infection rather than vaccination.
Seven (2.3 %) of all vaccinated individuals were reactive to HBsAg, indicating infection.
Individuals having ages < 15 years had the highest immune response (89.8 %) with antibody level ≥10 mIU / ml.
There was no difference in response at ages from 16-35 (82.8 %), while the lowest response was obtained at ages > 36 years (66.7 %).
The present study included two vaccination schedules, the first one at 0, 1, 2 months, showing an immune response of 62.2 %, while the second schedule at 0, 1, 6 months showed a greater immune response of 83.1 %.
Individuals immunized with a yeast-derived vaccine had higher anti-HBs levels (81.9 %), than those immunized with a plasma-derived vaccine (79.8 %).
The year intervals (1-5 years) after primary immunization showed no difference in the immune response.
Conclusion : This study revealed a high response rate to the vaccine.
However, a considerable proportion of vaccinated individuals remain to be reconsidered for either revaccination or booster doses due to nonexistent, inadequate, or low response.
The schedule of 0, 1, and 6 months was more efficient in inducing antibodies towards the vaccine than the 0, 1, 2 months schedule.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Shamahi, Hasan Abd al-Wahhab& al-Moyed, Tageia Abd al-Karim& al-Medhagi, Anwar G.. 2009. Evaluation of the immune response to hepatitis b vaccine in different age groups of the population of sana’a-Yemen. Journal of the Bahrain Medical Society،Vol. 21, no. 1, pp.201-206.
https://search.emarefa.net/detail/BIM-238380
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Shamahi, Hasan Abd al-Wahhab…[et al.]. Evaluation of the immune response to hepatitis b vaccine in different age groups of the population of sana’a-Yemen. Journal of the Bahrain Medical Society Vol. 21, no. 1 (Mar. 2009), pp.201-206.
https://search.emarefa.net/detail/BIM-238380
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Shamahi, Hasan Abd al-Wahhab& al-Moyed, Tageia Abd al-Karim& al-Medhagi, Anwar G.. Evaluation of the immune response to hepatitis b vaccine in different age groups of the population of sana’a-Yemen. Journal of the Bahrain Medical Society. 2009. Vol. 21, no. 1, pp.201-206.
https://search.emarefa.net/detail/BIM-238380
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 206
رقم السجل
BIM-238380
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)