Pattern of small intestinal mucosal changes in patients with type 1 diabetes mellitus

الملخص EN

Background : The coexistence of type 1 diabetes mellitus (DM) and Celiac disease (CD) is well recognized with a prevalence of CD in type 1 DM reported to be between 0 % and 10.4 %.

The aim of this study was to find the pattern of small intestinal mucosal changes in patients with type 1 DM.

Methods : A cross sectional study done in Al-Faiha hospital in Basrah, Iraq, on patients with type 1 DM.

Duodenoscopy was done and at least four biopsies were taken from the second part of the duodenum.

Results : Four patients had normal biopsy, 16 patients had duodenitis, and 10 patients had Marsh type I.

Marsh type IIIA were seen in 4 patients, Marsh IIIB were seen in two patients, and Marsh IIIC in 4 patients.

Marsh IIIB and C histology were regarded compatible with CD, so the incidence of CD was 15 %.

Conclusion : All patients with type 1 DM should be screened for CD.

Duodenal biopsy is a relevant tool for screening CD in patients with type I DM.