Dynamics of blood biochemistry and haematology in the spiny-tailed lizard (uromastyx microlepis)‎

الملخص EN

Reference values for some serum biochemical and some hematological parameters were examined in the spiy-tailed lizard Uromastyx microlepis and a comparison was made between captive and free-living animals and with other reptiles and mammals.

A total of 24 animals were used.

The variables examined include glucose, urea, creatinine, uric acid, aspartate and alanine aminotransferases, alkaline phosphates, lactate dehydrogenase, creatine kinas, amylase, total and direct bilirubin, total protein, albumin, A / G ratio, cholesterol, triglycerides, sodium, potassium, calcium, phosphorus, magnesium, iron, osmolality, %glycation of haemoglobin, leucocyte and erythrocyte counts, haemoglobin concentration, haematocrit, haematimetric indices, differential count and erythrocyte osmotic fragility test.

Also determined were the blood pH, and gases, CO2, pO2, [HC03'] [CO2] and %02 saturation.

Only three parameters exhibited statistically significant (P < 0.05) differences between the two populations investigated.

The captive animals showed higher serum glucose and lower alkaline phosphates and creative kinase levels.

The results were compared to those in other reptiles and to mammalian species.

Low urea concentration (0.22 ± O.19 mM), high amylase(1573.38± 411.78 U / l) and osmolality (340.09 ± 39.91mOsm / kg.HzO) levels were found in both captive and free animals.

The red blood cells were less fragile with (10% lysis) compared to human red cells (80% lysis) at the same NaCl concentration of 0.4g%.

The blood pH (7.27±0.2)and gases were indicative of an acidic blood.