The correlation between lactate dehydrogenase, creatine kinase and total thiol levels in sera of patients with β-thalassemia

الملخص EN

Lactate dehydrogenase (LDH), creatine kinase (CK) activities and total thiol levels had been measured in serum samples for 30 β-Thalassemia patients, aged 7-35 years who had been treated at Thalassemia center in the Babylon Maternity and children Hospital for the period between April 2008 to July 2008, compared with 30 healthy controls aged 7-35 years.

The purpose of this study was to investigate the activity of these enzymes and the levels of total thiol in β-Thalassemia patients as indicators of the relationship between these parameters and complication of Thalassemia.

There was a significant increase of LDH, no significant decrease of CK activity.

There was no statistical significant difference between patients and controls as regards to total thiol levels.