Study of some purine metabolic enzymes in sera of patients with renal failure

الملخص EN

one hundred seven patients (51 male and 56 females) suffering from renal failure admitted to Mirjan Teaching Hospital were included.

Twenty healthy individuals were included as control group.

Blood samples were collected and the sera were separated.

It was found that renal failure was more predominant among the patients age group rang from 40– 70 years old.

Besides, it was found out that mean values of some biochemical parameters importance for the detection of the disease which were investigated in this study where higher than the normal.

It was found that urea and creatinine mean value for all patients were highly significant if compared to control group.

The mean value (M ± SD) of Adenosine deaminase activity was decreased significantly (14.30 ± 10.47) in all patients with renal failure if compared to the control group (63.80 ± 22.98).

On the other hand, the mean of xanthine oxidase activities also reduced but not significantly (4453.98 ± 694.86) if compared with control group ( 4669.45 ± 811.80 ).