Probiotic effects of feeding live lactobacillus acidophilus to candida albicans-colonized oral cavity of rats

الملخص EN

This study investigates the antagonism activity of Lactobacillus acidophilus against the yeast Candida albicans in vitro.

Results revealed that L.

acidophilus with high antagonism activity and inhibited growth of C.

albicans.

Amodel for oral candidiasis in BALB / c rats was established.

After inoculation with 1 × 108 C.

albicans yeasts, these rats displayed increased levels of oral colonization; oral thrush appeared after 4 days of infection.

Rats were fed live L.

acidophilus for assessing its capacity to control the oral infection by elimination the yeast from the oral cavity.

Data showed that feeding live L.

acidophilus for 15 days significantly shortened the duration of oral colonization compared to control animals