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Assessment of cardiac functions in children with sickle cell disease
المؤلفون المشاركون
Ghanim, Sabri
al-Kholia, Usamah M.
Ali, Yasir F.
Mansur, Mustafa
Abd al-Monem, Nermin
المصدر
Egyptian Pediatric Association Gazette
العدد
المجلد 58، العدد 3 (31 يوليو/تموز 2010)، ص ص. 23-30، 8ص.
الناشر
تاريخ النشر
2010-07-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Background: Sickle cell disease (SCD) is an inherited disorder associated with significant morbidity, characterized by the presence of abnormal hemoglobin within the red blood cells.
The cardiovascular system is stressed by chronic anemia, small pulmonary artery occlusions and myocardial hemosiderosis that cause multiple anatomical and functional changes. Aim : Anatomical and functional cardiac assessment through M mode, 2 dimension and Doppler echocardiography in pediatric patients with sickle cell anemia (SCA).
Methods: Forty children with SCA, 24 males and 16 females, of mean ages 10 ± 3.4 years admitted to Al jeddani hospital, Jeddah, Saudi Arabia with proven diagnosis of SCA were included in the study.
In addition, thirty age and sex matched healthy children were served as a control group.
All children were subjected to history taking, clinical examination and routine laboratory investigations (CBC, hemoglobin electrophoresis and serum ferritin) as well as M mode, 2 dimension and Doppler echocardiography. Results : patients with SCD had higher left ventricular end diastolic dimension, left atrial dimension, stroke volume and left ventricular mass compared to control group.
Mild pulmonary hypertension with mean pulmonary artery systolic pressure (PASP) of 30 ± 5.40 mmHg was observed in patients with SCD.
Conclusion: Chamber dilations, left ventricular hypertrophy with increased left ventricular mass associated with left ventricular diastolic dysfunction secondary to chronic anemia with volume overload and sickle cell cardiomyopathy confirm the evidence of the literature in characterizing a sickle cell disease in pediatrics.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Kholia, Usamah M.& Abd al-Monem, Nermin& Ali, Yasir F.& Ghanim, Sabri& Mansur, Mustafa. 2010. Assessment of cardiac functions in children with sickle cell disease. Egyptian Pediatric Association Gazette،Vol. 58, no. 3, pp.23-30.
https://search.emarefa.net/detail/BIM-248886
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Monem, Nermin…[et al.]. Assessment of cardiac functions in children with sickle cell disease. Egyptian Pediatric Association Gazette Vol. 58, no. 3 (Jul. 2010), pp.23-30.
https://search.emarefa.net/detail/BIM-248886
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Kholia, Usamah M.& Abd al-Monem, Nermin& Ali, Yasir F.& Ghanim, Sabri& Mansur, Mustafa. Assessment of cardiac functions in children with sickle cell disease. Egyptian Pediatric Association Gazette. 2010. Vol. 58, no. 3, pp.23-30.
https://search.emarefa.net/detail/BIM-248886
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 29-30
رقم السجل
BIM-248886
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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