Primary splenic hodgkin’s disease in a patient with chronic granulomatous disease : a case report

الملخص EN

Here we report a 20-year-old male, a known case of chronic granulomatous disease (CGD), who presented with fever and splenomegaly.

After splenectomy, primary splenic Hodgkin’s disease was diagnosed.

Immunohistochemistry confirmed the diagnosis (positive CD15 and CD30).

With chemotherapy, his fever was subsided and now after 6 months, he is doing well.

Although primary immune deficiencies have been reported to show an increased tendency to develop malignancies, until now there has been no report of a patient with CGD and Hodgkin’s disease.