Estimation of immunoglobulins and complement component C3 and C4 in some patients with hodgkin and non-hodgkin lymphoma in Basrah governorate

الملخص EN

The humeral immune response including serum Immunoglobulin's (lgG, IgM and IgA) and complement components (C3 and C4) level in Hodgkin (HL) and Non-Hodgkin (NHL) Lymphoma patients were studied.

Forty five samples were taken (20 NHL, 10 HL.

15 control).

Examined by single Radial Immunodiffusion assay (SRlD).

The results showed a non-significant elevation of 1gG level in the sera of HL & NHL patients 1097.9 mg / d1 and 1088.3 mg / dl.

respectively, in comparison with control group ( 950.7 mg / d1); Non significant elevation of IgM level also had been reported in the sera of HL & NHL patients 232.71 mg / dl and 228.6 mg / dl.

Respectively, while it reached 166.78 mg/dl in control group.

The results revealed a non-significant decrease in IgA level in the sera of HL patients (227.2 mg / dl) while NHL patients showed non-significant elevation of it ( 324.1 mg / dl) while it reached 304.3 mg/dl in control group.

There was a non-significant decrease in complement component C4 level in the sera of HL patients 21.331 mg / dl while NHL patients showed non-significant and slightly increase of it 25.565 mg / dl ) in comparison with the mean value of the control group which reached 24.9 mg / dl.

complement component C3 level was non significantly increase in the sera of HL patios 141.98 mg/dl while NHL patients showed non-significant decrease in complement component level 116.66 mg / dl in comparison with the mean value of the control group which reached Ui mg / dl.