Synthesis characterization of new compounds derivatives from amino acids Alanin, Argenine and Aspartic acid

الملخص EN

This work involves preparation many compounds from cyclization of amino acid (Alanin, Argenine and Aspartic acid) by acetic an hydride to give (1-3) compounds, the last react with hydrazine to give its derivatives 1-amino -1-H–imidazol 5 (4H) one.

Schiff’s bases was prepared from react (4-6) compound with various aldehydes and ketones ethyl bromo acetate react with (4-6) will be prepare (15-17) which react with hydrazine to give hydrazide derivatives (18-20) which condensation with aldehyde to keton to form Schiff’s bases (21- 25).

on the other side compounds (15-17) react with thiosemicarbazide to obtain (26-28) which convert to (24-30) by deal with H2SO4 and to (31-33) by react with Sodium hydroxide.