Serum YKL-40 in rheumatoid arthritis and its correlation with disease activity
المؤلفون المشاركون
al-Shami, Hibah Allah Ahmad
Khalid, Hinaz Faruq
Nasr, Mahmud al-Tayyib
Sulayman, Dina Muhammad Ibrahim
المصدر
Egyptian Rheumatology and Rehabilitation
العدد
المجلد 35، العدد 2 (30 إبريل/نيسان 2008)، ص ص. 211-220، 10ص.
الناشر
الجمعية المصرية للروماتيزم و التأهيل
تاريخ النشر
2008-04-30
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective : To determine the serum level of YKL-40 in rheumatoid arthritis (RA) patients and to find out its correlation with the disease activity.
Methodology : The study was conducted on 20 RA patients recruited from the Rheumatology and Rehabilitation Department of Ain Shams University Hospitals, as well as 10 apparently healthy individuals who served as a control group.
Patients with liver disease, myocardial infarction or malignancies were excluded.
Also patients taking slow-acting drugs or had intra-articular injections in the previous month before the study were not included.
All the patients and the controls were subjected to complete history taking, thorough clinical examination, radiological and laboratory tests.
Serum YKL-40 level was measured in the patients and the controls using ELISA test.
Results : Serum YKL-40 level was significantly higher in RA patients as compared to the control group.
Serum YKL-40 level showed a positive significant correlation with the disease duration, the parameters of disease activity in RA patients and with the disease severity as assessed with Larsen's radiological score.
Conclusions : Measurement of serum YKL-40 level in RA patients is a laboratory test that can be used as a new parameter other than the conventional markers of inflammation, which are ESR and serum CRP level.
Also, it helps to assess the disease activity as well as the progression and the destructive effect of the disease on the joints.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nasr, Mahmud al-Tayyib& Khalid, Hinaz Faruq& al-Shami, Hibah Allah Ahmad& Sulayman, Dina Muhammad Ibrahim. 2008. Serum YKL-40 in rheumatoid arthritis and its correlation with disease activity. Egyptian Rheumatology and Rehabilitation،Vol. 35, no. 2, pp.211-220.
https://search.emarefa.net/detail/BIM-26671
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nasr, Mahmud al-Tayyib…[et al.]. Serum YKL-40 in rheumatoid arthritis and its correlation with disease activity. Egyptian Rheumatology and Rehabilitation Vol. 35, no. 2 (Apr. 2008), pp.211-220.
https://search.emarefa.net/detail/BIM-26671
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nasr, Mahmud al-Tayyib& Khalid, Hinaz Faruq& al-Shami, Hibah Allah Ahmad& Sulayman, Dina Muhammad Ibrahim. Serum YKL-40 in rheumatoid arthritis and its correlation with disease activity. Egyptian Rheumatology and Rehabilitation. 2008. Vol. 35, no. 2, pp.211-220.
https://search.emarefa.net/detail/BIM-26671
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 219-220
رقم السجل
BIM-26671
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر