Prevalence of mixed hepatitis C virus (HCV) genotypes among recently diagnosed dialysis patients with HCV infection
المؤلف
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 22، العدد 4 (31 أغسطس/آب 2011)، ص ص. 712-716، 5ص.
الناشر
تاريخ النشر
2011-08-31
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Hepatitis C virus (HCV) infection is considered a major health problem recognized globally.
HCV is a major cause of chronic liver disease that may lead to cirrhosis and hepatocellular carcinoma.
The aim of this study was to investigate the prevalence of multiple (mixed) HCV genotypes in Saudi patients recently diagnosed with HCV infection and their association with various clinical risk factors.
We examined a total of 1, 292 newly diagnosed HCV-positive cases between January 2006 and July 2009 at the Molecular Pathology Laboratory, King Abdulaziz Medical City, Riyadh.
The clinical and laboratory data of the study patients were collected.
The HCV-RNA viral load and its genotyping were carried out with RT-PCR technology to assist in the follow-up and management of HCV-infected patients undergoing antiviral therapy.
Twenty-two patients (1.7%) were found to have mixed HCV genotypes; of them, mixed genotypes associated with genotype-4 were seen in 19 patients (86%), mixed genotypes associated with genotype-1 were found in 68.4%, with genotype-3 in 26.3% and with genotype-2 in 5.3%.
Additionally, mixed genotypes associated with genotype-1 were seen in three cases (13.6%); they were associated with genotype-2 in two (66.7%) and with genotype-5 in one patient (33.3%).
In conclusion, the prevalence rate of mixed HCV genotypes in the cohort of the newly infected Saudi patients was 1.7%, with genotype-4 being the most frequent genotype encountered.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Balwi, Muhammad A.. 2011. Prevalence of mixed hepatitis C virus (HCV) genotypes among recently diagnosed dialysis patients with HCV infection. Saudi Journal of Kidney Diseases and Transplantation،Vol. 22, no. 4, pp.712-716.
https://search.emarefa.net/detail/BIM-268208
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Balwi, Muhammad A.. Prevalence of mixed hepatitis C virus (HCV) genotypes among recently diagnosed dialysis patients with HCV infection. Saudi Journal of Kidney Diseases and Transplantation Vol. 22, no. 4 (Aug. 2011), pp.712-716.
https://search.emarefa.net/detail/BIM-268208
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Balwi, Muhammad A.. Prevalence of mixed hepatitis C virus (HCV) genotypes among recently diagnosed dialysis patients with HCV infection. Saudi Journal of Kidney Diseases and Transplantation. 2011. Vol. 22, no. 4, pp.712-716.
https://search.emarefa.net/detail/BIM-268208
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 715-716
رقم السجل
BIM-268208
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر