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HIV-Associated immune complex glomerulonephritis with "lupus-like" features
المؤلفون المشاركون
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 22، العدد 4 (31 أغسطس/آب 2011)، ص ص. 769-773، 5ص.
الناشر
تاريخ النشر
2011-08-31
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Renal structural abnormalities in HIV / AIDS infected patients have been infrequently and incompletely reported in patients from sub-Saharan Africa.
We report an immune complex glomerulonephritis with "lupus-like" features in a ten-year-old HIV+ boy who was evaluated at the University Hospital of Kinshasa.
The light microscopic examination of the renal biopsy displayed a predominantly membranoproliferative glomerulonephritis with prominent focal segmental necrotizing injury, numerous wire-loops, and a spiky membranous nephropathy.
In addition, there was prominent tubular injury, micro cysts filled with periodic acid-Schiff (PAS) Renal structural abnormalities in HIV / AIDS infected patients have been infrequently and incompletely reported in patients from sub-Saharan Africa.
We report an immune complex glomerulonephritis with "lupus-like" features in a ten-year-old HIV+ boy who was evaluated at the University Hospital of Kinshasa.
The light microscopic examination of the renal biopsy displayed a predominantly membranoproliferative glomerulonephritis with prominent focal segmental necrotizing injury, numerous wire-loops, and a spiky membranous nephropathy.
In addition, there was prominent tubular injury, micro cysts filled with periodic acid-Schiff (PAS) positive casts, edema and an inflammatory infiltrate of the interstitial, features of a classic HIV-associated nephropathy (HIVAN).
Electron microscopy revealed large sub endothelial, intra-membranous, sub epithelial and meningeal deposits.
The combination of these findings, while being consistent with lupus nephritis WHO grade IV/V, the tubulointerstitial HIVAN-like changes and the absence of clinical evidence of lupus disease favored an HIV-associated immune complex glomerulonephritis with "lupus-like features".
Positive casts, edema and an inflammatory infiltrate of the interstitial, features of a classic HIV-associated nephropathy (HIVAN).
Electron microscopy revealed large sub endothelial, intra-membranous, sub epithelial and meningeal deposits.
The combination of these findings, while being consistent with lupus nephritis WHO grade IV/V, the tubulointerstitial HIVAN-like changes and the absence of clinical evidence of lupus disease favored an HIV-associated immune complex glomerulonephritis with "lupus-like features."
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pakasa, Nestor M.& Binda, Pm.. 2011. HIV-Associated immune complex glomerulonephritis with "lupus-like" features. Saudi Journal of Kidney Diseases and Transplantation،Vol. 22, no. 4, pp.769-773.
https://search.emarefa.net/detail/BIM-268271
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pakasa, Nestor M.& Binda, Pm.. HIV-Associated immune complex glomerulonephritis with "lupus-like" features. Saudi Journal of Kidney Diseases and Transplantation Vol. 22, no. 4 (Aug. 2011), pp.769-773.
https://search.emarefa.net/detail/BIM-268271
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pakasa, Nestor M.& Binda, Pm.. HIV-Associated immune complex glomerulonephritis with "lupus-like" features. Saudi Journal of Kidney Diseases and Transplantation. 2011. Vol. 22, no. 4, pp.769-773.
https://search.emarefa.net/detail/BIM-268271
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 772-773
رقم السجل
BIM-268271
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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