Evaluation of the HCV core antigen assay as a second-line supplemental test for diagnosis of active hepatitis C infection
المؤلفون المشاركون
Rajih, Ibrahim
Abd al-Aziz, Majidah
Abd al-Rahman, Suhayr
al-Sharnubi, Amal
al-Sharawi, Ahmad
المصدر
Tanta Medical Sciences Journal
العدد
المجلد 2، العدد 1 (31 مارس/آذار 2007)، ص ص. 6-14، 9ص.
الناشر
تاريخ النشر
2007-03-31
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الموضوعات
الملخص EN
Background/Aim : hepatitis C virus core (HCV) antigen assays have been produced to exclude infectious donations collected the preseroconversion window phase.
For the same purpose, we evaluated the specificity and sensitivity of a novel hepatitis C virus core antigen detection immunoassay and the applications of this assay in clinical diagnosis.
Patients & Methods : samples were collected from 30 anti-HCV antibody negative healthy subjects (Gl, and 46 anti-HCV antibody positive patients (G2.
All included samples were subjected to HCV core antigen and HCV-RNA PCR.
Results : Among the 46 anti-HCV Ab positive samples, HCV core antigen was positive in 38 samples from 40 samples positive for HCV-RNA with sensitivity of 95 % (38 / 40).
All the 30 anti-HCV Ab negative samples (n = 30 were negative for both HCV core antigen and HCV-RNA with specificity of 100 %.There was no significant variation in the sensitivity of HCV core antigen between genotype 1 (100 %) and genotype 4 (94.5 %).
Viral load n HCV core antigen positive samples (906653+133803 was significantly increased than that of HCV core antigen negative samples (16342 + 5245) with P value < 0.05.
Conclusion : HCV core antigen assay is a useful method in screening strategy of HCV infection and provides a reliable means of distinguishing between current and cleared HCV infections that is well correlated with HCV-RNA testing.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Sharawi, Ahmad& Abd al-Aziz, Majidah& Abd al-Rahman, Suhayr& Rajih, Ibrahim& al-Sharnubi, Amal. 2007. Evaluation of the HCV core antigen assay as a second-line supplemental test for diagnosis of active hepatitis C infection. Tanta Medical Sciences Journal،Vol. 2, no. 1, pp.6-14.
https://search.emarefa.net/detail/BIM-269517
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Rahman, Suhayr…[et al.]. Evaluation of the HCV core antigen assay as a second-line supplemental test for diagnosis of active hepatitis C infection. Tanta Medical Sciences Journal Vol. 2, no. 1 (Mar. 2007), pp.6-14.
https://search.emarefa.net/detail/BIM-269517
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Sharawi, Ahmad& Abd al-Aziz, Majidah& Abd al-Rahman, Suhayr& Rajih, Ibrahim& al-Sharnubi, Amal. Evaluation of the HCV core antigen assay as a second-line supplemental test for diagnosis of active hepatitis C infection. Tanta Medical Sciences Journal. 2007. Vol. 2, no. 1, pp.6-14.
https://search.emarefa.net/detail/BIM-269517
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 13-14
رقم السجل
BIM-269517
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر