Synthesis,structural and biological studies of 4-[(1-phenyl-2, 3-dimethyl-3-pyrozoline-5-one)‎azo]-n, n-dimethyl anline with some transition metal ions

الملخص EN

The present work includes the preparation and characterization of {Co (II), Ni (II), Pd (II), Fe (III) , Ru (III),Rh (III), Os (III) , Ir (III) , Pt (IV) and VO(IV)}complexes of a new ligand 4-[(1-phenyl-2, 3-dimethyl-3-pyrozoline-5-one) azo]-N, N-dimethylanline (PAD).

The product (PAD) was isolated, studies and characterized by physical measurements, i.e., (FT-IR), (UV) Spectroscopy and elemental analysis (C.H.N).

The prepared complexes were identified and their structural geometric were suggested in solid state by using flame atomic absorption, elemental analysis (C.H.N), (FT-IR) and (UV-Vis) Spectroscopy, as well as magnetic susceptibility and conductivity measurements.

The study of the nature of the complexes formed in (ethanol solution) following the mole ratio method, gave results which were compared successfully with those obtained from solid state studies.

The apparent stability constant of the complexes have been studied with the time and their color were stable for more than (6) hours, as well as the molar absorptivity's have been calculated.

The antibacterial activity for the ligand (PAD) and their metal complexes were studied against two selected micro-organisms [(Klesbiella pneumonia) as gram negative] and [(Streptococcus facials) as gram positive].

Furthermore the antifungal activity against two micro-organisms (Candida albinos and Aspergillums flatus) was studied for the ligand (PAD) and their metal complexes.