Efficacy of HBV vaccination in children with thalassemia major, south Khorasan, Iran
المؤلف
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 11، العدد 3 (31 يوليو/تموز 2009)، ص ص. 318-320، 3ص.
الناشر
تاريخ النشر
2009-07-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
3
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : thalassemia patients are more susceptible to hepatitis than the normal population due to the frequent blood transfusion.
This study was performed to determine the immune response of children with major β-thalassemia, by measuring anti-HBS antibody following the last HBV vaccine injection.
Methods : this study was carried out on all thalassemic children under the care of Iran Thalassemia Foundation (38 cases) in Birjand, receiving three standard intramuscular recombinant HBV vaccines.
The children’s mean age was 9.2 ± 4.6 years.
Based on the time elapsed since their last vaccine injection, the subjects were divided into two groups of ≤ 5 years and > 5 years.
Based on the serum level of anti-HBS-antibody, the subjects were categorized as good responders (anti-HBS > 100 IU / lit), low (anti-HBS = 10-100 IU / lit), and non-responders (anti-HBS < 10 IU / lit Results : the mean ranges of anti-HBS level in the above-mentioned groups were 99.7 and 43.3 IU / lit, respectively.
Out of 38 individuals, 13 (34.2 %) were good responders, 9 (23.7 %) low and 16 (42.1 %) non responders.
Conclusion : standard HBV vaccination in thalassemic children results in an immune response in 57.9 % of subjects.
Therefore, assessment of anti-HBS-antibody 5 years after the last vaccination is recommended.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Azarkar, Z.. 2009. Efficacy of HBV vaccination in children with thalassemia major, south Khorasan, Iran. Iranian Red Crescent Medical Journal،Vol. 11, no. 3, pp.318-320.
https://search.emarefa.net/detail/BIM-27366
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Azarkar, Z.. Efficacy of HBV vaccination in children with thalassemia major, south Khorasan, Iran. Iranian Red Crescent Medical Journal Vol. 11, no. 3 (Jul. 2009), pp.318-320.
https://search.emarefa.net/detail/BIM-27366
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Azarkar, Z.. Efficacy of HBV vaccination in children with thalassemia major, south Khorasan, Iran. Iranian Red Crescent Medical Journal. 2009. Vol. 11, no. 3, pp.318-320.
https://search.emarefa.net/detail/BIM-27366
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 320
رقم السجل
BIM-27366
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر