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Evaluation of the value of combined urine cytology and cystoscopy for follow-up of superficial transitional cell carcinoma of the urinary bladder
المؤلفون المشاركون
Muhammad, Dalia B.
Tahun, Nifin S.
Abd al-Maqsud, Abd al-Maqsud M.
المصدر
Journal of the Egyptian National Cancer Institute
العدد
المجلد 22، العدد 2 (30 يونيو/حزيران 2010)، ص ص. 105-111، 7ص.
الناشر
جامعة القاهرة المعهد القومي للأورام
تاريخ النشر
2010-06-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective: Cystoscopic biopsy is the most accurate technique used to assess the efficacy of treatment and to detect recurrence of superficial TCC of urinary bladder.
Implementation of voided urine cytology to detect tumor cells in urine samples may represent an additional tool.
The aims of this study are : (1) to estimate the reliability of combined cystoscopy and urine cytology examination in the follow-up of cases of superficial urinary bladder carcinoma, which might help to restrict cystoscopy biopsies for these cases with its morbidity and cost, (2) To discuss the diagnostic pitfalls of cytological examination in these cases.
Patients and Methods : this is a prospective study, on 93 patients with superficial TCC of urinary bladder who were initially treated by complete TUR with or without adjuvant intravesical therapy with Bacillus Chalmette Guerin (BCG) (120mg / instillation) for 6 weeks.
Cystoscopy findings, urine cytology and histologic results of cystoscopy biopsies were assessed.
Results : by histologic examination, 41 (44 %) cases were recurrent TCC and 52 (56 %) were reported as negative for recurrence.
By cystoscopy examination there were 36 positive cases, 4 of them were false positive.
Out of the 57 negative cases for recurrence cystoscopically, 9were histologically positive and were considered as false negative results.
By cytology, 28 cases were positive, 3 were false positive, and 65 were negative for recurrence, 16 of them were false negative.
Most of false negative cases were low grade TCC.
Sensitivity of cytology and cystoscopy in the detection of recurrence was 61 % and 78 % ; respectively.
When the two examinations were combined, sensitivity was 100 %, and specificity Was 92.3 %.
Conclusion : for follow-up of superficial bladder carcinoma, the combination of negative cystoscopy find-ings and negative urine cytology may replace routine biopsies with their morbidity and cost.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tahun, Nifin S.& Abd al-Maqsud, Abd al-Maqsud M.& Muhammad, Dalia B.. 2010. Evaluation of the value of combined urine cytology and cystoscopy for follow-up of superficial transitional cell carcinoma of the urinary bladder. Journal of the Egyptian National Cancer Institute،Vol. 22, no. 2, pp.105-111.
https://search.emarefa.net/detail/BIM-273798
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Maqsud, Abd al-Maqsud M.…[et al.]. Evaluation of the value of combined urine cytology and cystoscopy for follow-up of superficial transitional cell carcinoma of the urinary bladder. Journal of the Egyptian National Cancer Institute Vol. 22, no. 2 (Jun. 2010), pp.105-111.
https://search.emarefa.net/detail/BIM-273798
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tahun, Nifin S.& Abd al-Maqsud, Abd al-Maqsud M.& Muhammad, Dalia B.. Evaluation of the value of combined urine cytology and cystoscopy for follow-up of superficial transitional cell carcinoma of the urinary bladder. Journal of the Egyptian National Cancer Institute. 2010. Vol. 22, no. 2, pp.105-111.
https://search.emarefa.net/detail/BIM-273798
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 110-111
رقم السجل
BIM-273798
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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