Treatment of otomycosis : a comparative study using miconazole cream with clotrimazole otic drops

الملخص EN

Objective : this study was conducted to compare the use of two different antifungal agents from the azoles family; Miconazole cream applied topically on the skin of the external canal and tympanic membrane and Clotrimazole otic drops.

Methods : Ninety patients aged (12-72) years who presented with otomycosis at Prince Hashim Hospital in Zarka between October 2007 to June 2009 were enrolled in this study.

Patients were divided into two groups, group a (48 patients) : patients were treated by toileting and application of Miconazole cream, group B (42 patients) : patients were treated by toileting and using Clotrimazole 1 % (otozol) otic drops.

Patients followed after one and two weeks.

One way ANOVA test was used to calculate the significant differences at P < 0.05 between the means of the study treatment groups.

Results : Patients in group A (Miconazole) showed a better response to treatment in comparison to patients in group B (Clotrimazole drops).

Conclusion: Although the two treatment regimens showed no statistically significant difference due to the small number of cases, Micanazole cream after toileting is a better choice due to its lower cost and better compliance.