L-asparaginase therapy with concomitant cranial venous thrombosis : can mri help avoiding stroke
المؤلف
المصدر
Journal of the Egyptian National Cancer Institute
العدد
المجلد 21، العدد 1 (31 مارس/آذار 2009)، ص ص. 43-50، 8ص.
الناشر
جامعة القاهرة المعهد القومي للأورام
تاريخ النشر
2009-03-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Purpose: To prospectively use MRI in the early detection of intracranial sino-venous thrombosis during the L-asparaginase induction therapy of acute leukemia thus preventing the evolution of brain venous infarct.
Materials and Methods : the study population consisted of seventy patients receiving L-asparaginase induction therapy for acute leukemia in the National Cancer Institute of Cairo University presenting with clinical neurological signs suggestive of aseptic intracranial venous thrombosis.
All the patients were studied by 1.5 Tesla magnet using conventional MRI pulse sequences and MR venography studies.
The imaging findings were processed as regards the detection of venous thrombosis, its signal criteria and the evaluation of any companion brain parenchymal ischemic insults.
Results: Eleven patients were diagnosed with dural venous sinus thrombosis with subsequent specific signal pattern of the thrombus that could be linked to the duration of thrombosis.
The MR venography studies detected the thrombosis in nine cases out of eleven.
Ten cases scored brain parenchymal signal abnormality that could indicat infarction, eight of them were hemorrhagic in nature.
Conclusion : L-asparaginase therapy is accompanied by high risk of venous thrombosis that could involve the intra-cranial sino-venous structures.
MRI could be used effectively in the early diagnosis of such serious, curable complication using a combination of conventional spin echo pulse sequences and MR venography studies.
Hemorrhagic venous infarcts should draw the attention to underlying established venous thrombosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Urabi, Ala M.. 2009. L-asparaginase therapy with concomitant cranial venous thrombosis : can mri help avoiding stroke. Journal of the Egyptian National Cancer Institute،Vol. 21, no. 1, pp.43-50.
https://search.emarefa.net/detail/BIM-274020
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Urabi, Ala M.. L-asparaginase therapy with concomitant cranial venous thrombosis : can mri help avoiding stroke. Journal of the Egyptian National Cancer Institute Vol. 21, no. 1 (Mar. 2009), pp.43-50.
https://search.emarefa.net/detail/BIM-274020
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Urabi, Ala M.. L-asparaginase therapy with concomitant cranial venous thrombosis : can mri help avoiding stroke. Journal of the Egyptian National Cancer Institute. 2009. Vol. 21, no. 1, pp.43-50.
https://search.emarefa.net/detail/BIM-274020
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 49-50
رقم السجل
BIM-274020
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر