The effect of matrix metalloproteinase inhibitor on bond durability of resin composite and giomer restorations to dentin (in-vivo study)‎

الملخص EN

Objective:This in vivo study was carried out to evaluate the effect of chlorhexidine pretreatment on the durability of bonded resin composite restoration and giomer restorations as assessed by microtensile bond strength testing.

Materials and methods: The study protocol involving dogs was performed at the faculty of veterinary medicine, Cairo University.

A total number of eight young healthy dogs, aged between one & two years old with an average weight of 10 Kg were used in this study.

The study was divided into four phases at different time intervals; after 24 hours, three months, six months and nine months.

One experimental dog was enrolled within each phase.

A two step etch-and- rinse adhesive system (Adper Single Bond 2) was used with nanofilled resin composite and giomer restorative materials with and without chlorhexidine pretreatment.

All premolars and molars dogs’ teeth of the experimental dogs of each phase of the study were subjected to the different predetermined treatment modalities .This experimental study design was performed to obtain a total of 80 premolars and molars dogs’ teeth (sample size n = 5 teeth per each subdivision).

Dogs were sacrificed after the specified testing period.

The teeth were separated from the jaws by the use of saw.

Teeth were mounted on the cutting machine, and sectioned into slabs and then into beams of cross sectional area of 1 mm2.

For microtensile testing; each beam was fixed to a specially designed attachement and stressed in tension using universal Lloyd testing machine at a cross-head speed of 0.5 mm/minute until failure.

Microtensile bond strength values were tabulated and statistically analyzed.

Results: The analysis of variance ANOVA test revealed that with both Giomer and nanofilled resin composite when used with Adper Single Bond 2 without Consepsis, there was no statistically significant difference between means microtensile bond strengths after 24 hours, 3 months, 6 months and 9 months.

On the other hand, when Giomer was used with Adper Single Bond 2 with Consepsis, the mean microtensile bond strength after 24 hours showed the statistically significantly highest value.

This was followed by mean microtensile bond strength after 3 months.

There was no statistically significant difference between means microtensile bond strengths after 6 months and 9 months which showed the statistically significantly lowest values.

While, with Nanofilled resin composite and Adper Single Bond 2 with Consepsis, there was no statistically significant difference between means microtensile bond strengths after 24 hours, 3 months, 6 months and 9 months.

Conclusions: The bond performance of Adper Single Bond 2 deteriorates by time.

The use of 2% chlorhexidine gluconate (Consepsis) diminishes the loss of bond strength of Adper single Bond 2 over time up to certain limit.

The use of 2% chlorhexidine gluconate (Consepsis) was not able to completely prevent the loss of bond strengths over time.