Comparing the combination effect of propofol- ketamine and propofol-alfentanil on hemodynamic : stability during induction of general anesthesia inthe elderly
المؤلفون المشاركون
Kamali, K.
Joghataie, P.
Kamalipour, H.
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 11، العدد 2 (30 إبريل/نيسان 2009)، ص ص. 176-180، 5ص.
الناشر
تاريخ النشر
2009-04-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : propofol (Diprivan), a modern intravenous hypnotic drug, produces a reduction in both cardiac index (CI) and mean arterial pressure (MAP) due to its sympatholytic activity.
S-Ketamine (Ketanest), a potent analgesic, in contrast, causes an increase in both CI and MAP due to its sympathomimetic activity.
This study was performed to compare the combination effects of propofol-ketamine and propofol-alfentanil on hemodynamic stability during induction of general anesthesia.
Methods : In a prospective study, 100 patients over 60 (ASA I, II) scheduled for elective lower abdominal interventions were randomly divided into two groups.
For induction of general anesthesia, after injection of midazolam, the first group (A) received alfentanil and propofol and the second group (B) received S-ketamine and propofol.
Each group received atracurium as muscle relaxant.
Blood pressure (BP) and heart rate (HR) were measured before and 1 and 5 minutes after induction of anesthesia.
Results : the increase in HR and decrease in MAP were statistically significant in both groups 1 and 5 minutes after general anesthesia.
The increase in HR and decrease in MAP were significantly more in Group A, 1 and 5 minutes after general anesthesia.
Conclusion : the dose of S-ketamine administered during induction of general anesthesia may not be enough toneutralize the cardio-depressant effect of propofol.
A better hemodynamic activity was observed in Group compared to Group A due to partial neutralization of the opposing action.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kamalipour, H.& Joghataie, P.& Kamali, K.. 2009. Comparing the combination effect of propofol- ketamine and propofol-alfentanil on hemodynamic : stability during induction of general anesthesia inthe elderly. Iranian Red Crescent Medical Journal،Vol. 11, no. 2, pp.176-180.
https://search.emarefa.net/detail/BIM-27424
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kamalipour, H.…[et al.]. Comparing the combination effect of propofol- ketamine and propofol-alfentanil on hemodynamic : stability during induction of general anesthesia inthe elderly. Iranian Red Crescent Medical Journal Vol. 11, no. 2 (Apr. 2009), pp.176-180.
https://search.emarefa.net/detail/BIM-27424
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kamalipour, H.& Joghataie, P.& Kamali, K.. Comparing the combination effect of propofol- ketamine and propofol-alfentanil on hemodynamic : stability during induction of general anesthesia inthe elderly. Iranian Red Crescent Medical Journal. 2009. Vol. 11, no. 2, pp.176-180.
https://search.emarefa.net/detail/BIM-27424
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 179-180
رقم السجل
BIM-27424
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر