Role of grape seed extract as anti-hyperglycemia and antioxidant in experimental diabetic rats

الملخص EN

The anti-hyperglycemia and antioxidant effect of an aqueous extract of grape seed used in popular medicine in many countries of the world was studied in rats with streptozotocin induced diabetes.

Oral administration of grape seed extract (20 mg / 250 g rat body weight) for 30 days resulted in a significant reduction in glucose, GPT GOT, ALP and ACP.

The extract also causes a significant increase in reduced glutathione, in the liver and kidneys of rats with streptozotocin-induced diabetes.

These results clearly show the ant hyperglycemic and antioxidant property of grape seed extract.