دراسة التأثير السام لمعقد النحاس الثنائي مع المضاد الحيوي الدوكسيسايكلين في أنسجة الفئران المختبرية

الملخص EN

In this study, acute short toxicity test of copper (II) complex with Doxcycline was examined in 40 of the experimental mice by oral administer of the progressive doses during 72 hours .

Histopathological changes in the target organs were clearly evident , dose dependend and varying in severity from precipitate of the complex in the liver , kidney, lung , heart and spleen to the acute inflammation and necrosis in the liver ,lung , small and large intestine , while no Histopathological changes has seen in the brain .