Association between plasma lipoprotein (a) concentration and restenosis after stent implantation
المؤلف
المصدر
Tanta Medical Sciences Journal
العدد
المجلد 1، العدد 4 (31 ديسمبر/كانون الأول 2006)، ص ص. 6-16، 11ص.
الناشر
تاريخ النشر
2006-12-31
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الموضوعات
الملخص EN
Background / Aim : the plasma concentration of lipoprotein (a) [Lp(a)] is associated with atherosclerotic and thrombotic vascular diseases.
The aim of the present study was to evaluate the association between plasma Lp (a) concentration and in-stent restenosis.
Patients and Methods : One hundred and 9 patients with successful elective coronary stent implantation underwent follow-up angiography at 24 ± 6 weeks.
Restenosis after stent implantation occurred in 38 patients.
Results : univariate analysis showed that the reference diameter of the lesion was smaller in the restenosis group (2 : 93 + 0.29mm) than in the no-restenosis group (3.21 + 0.43 mm) (p < 0.05).
The lesion was longer in the restenosis group (14.2 ± 5.3 mm) than in the no-restenosis group (11.6 ± 4.9 mm) (p < 0.05).
Plasma Lp (a) concentrations in the restenosis group (30.5 + 23.9 mg / dl) were higher than in the no-restenosis group (16.9 ± 11.1 mg / dl) (p < 0.01).
Other lipid concentrations were similar in both groups.
Among the plasma Lp (a) concentrations, the rate of restenosis (71.4 %) in the high Lp(a) group (> 40 mg / dl) (n = 14) was greater compared with the other groups: 33.3% in the intermediate Lp (a) group (10-40 mg / dl) (n = 54), and 24.4 % in the low Lp (a) group (<10 mg / dl) (n = 41) (po.01).
The late loss (0.57+0.53 mm) in the low Lp (a) group was significantly less than the other groups : 0.88 ± 0.47mm in the intermediate Lp (a) group, and 1.08 ± 0.56 mm in the high Lp (a) group (p < 0.05).
In a multivariate regression model, plasma Lp (a) concentration remained significant as an independent predictor of restenosis in patients undergoing stent implantation (p = 0.020 odds ratio (OR) 1.37 95 %conficence interval (CI) 1.050-1.793), although the reference diameter (p-0.025 OR 0.23 95 %CI 0.061-0.830) and lesion length (p=0.021 OR 1.12 95 %CI 1.017-1.232) were related to stent restenosis.
Conclusions Plasma Lp (a) concentration is an independent risk factor of in-stent restenosis, although there is a relationship between the reference diameter, lesion length and restenosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Rashiedy, Tariq. 2006. Association between plasma lipoprotein (a) concentration and restenosis after stent implantation. Tanta Medical Sciences Journal،Vol. 1, no. 4, pp.6-16.
https://search.emarefa.net/detail/BIM-277498
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Rashiedy, Tariq. Association between plasma lipoprotein (a) concentration and restenosis after stent implantation. Tanta Medical Sciences Journal Vol. 1, no. 4 (Dec. 2006), pp.6-16.
https://search.emarefa.net/detail/BIM-277498
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Rashiedy, Tariq. Association between plasma lipoprotein (a) concentration and restenosis after stent implantation. Tanta Medical Sciences Journal. 2006. Vol. 1, no. 4, pp.6-16.
https://search.emarefa.net/detail/BIM-277498
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 14-16
رقم السجل
BIM-277498
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر