Pathological and bacteriological studies on diarrhea in ne born rabbits at Sharkia province

الملخص EN

In this work a total 150 rabbits (100 dead, 30 diseased and 20 apparently healthy) were obtained from private farms in Sharkia province.

The clinical signs of diseased rabbits were emaciation watery mucoid diarrhea and respiratory signs with mortality reached 70% in natural infection P.M.

examination revealed congestion and edema of the intestine beside congestion in all internal organs.

The bacteriological examination showed 97 (64.71 %) positive bacterial isolation of which 49 single isolate and 48 mixed infection which were tabulated in table 1.2.3.4.5 the predominant isolates were E.

coli 26 (26.81 %) and P.

multocida 19.52 %.

The Pathogenicity test was done for rabbits infected with E.

coli as showed in table (6).

The most isolated bacteria were highly sensitive to enroflaxocine and gentamycin.

Histopathologically examination in infected animals with E.

coli the intestine revealed congestion of sub mucosal blood vessels, mucinous degeneration with leukocyte infiltration of intestinal epi-thelium.

The lung showed congestion and thrombus in pulmonary blood vessels beside serofibrinous exudates with leuk-ocytic infiltration.

Moreover vacuolation of hepatocytes and congestion of hepatic blood vessels were observed.

In Pasteurella multocida infected animals revealed haemorrhages, broncho pneumonia, and interstitial pneumonia containing neutrophils.

Vacillation of hepatocytes, sub epithelial edema of glomerular epithelium ; cystic dilatation, and hyaline cast in renal tubules were observed.

Intestine showed leukocytes of the villus epithelium.

Congestion and hemorrhages in heart were observed It could be concluded that good management, hygienic measure, balanced ration and antibiotics for prevention and control of diarrhea in newly born rabbits must be done.