Kinetics of ruthenium (iii)‎ catalyzed oxidation of some amino acids by n-bromosuccinimide in acidic medium

الملخص EN

The kinetics and mechanism of Ru (III) catalyzed oxidation of asparagine and aspartic acid by N-bromosuccinimide (NBS) have been investigated in acidic medium in the presence of mercuric acetate as a scavenger in the temperature range 30° C-45° C.

The reactions follow identical kinetics.

The observed rate of oxidation is first order in [NBS], [Substrate] and [Ru (III)] respectively.

A small increase in rate is observed with increase in [KCI].

Additions of succinimide and acetic acid have retarding effect on the rate of oxidation.

Negligible effect of [Hg (OAc) 2], ionic strength and [H+] have been observed.

Various activation parameters have been calculated.

The mechanism of the reaction is discussed in terms of kinetic results.