Pattern visual evoked potential in response to monocular and binocular : stimulation in normal and amblyope subjects

الملخص EN

Background : Amblyopia is a relatively common condition with an incidence of 2-2.5 % in which visual acuity through an eye is subnormal despite no overt pathology.

The use of pattern visual evoked potential (P-VEP) has been the primary technique for electro physiologically detecting amblyopia in patients unable to undergo conventional testing.

This study was performed to evaluate the effectiveness of P-VEP parameters in amblyopic patients under monocular and binocular conditions.

Methods : Visual function was measured using P-VEP and Snellen acuity test in 30 children with amblyopia (12strabismic and 18 anisotropic amblyopic) and 30 visually normal control subjects.

Results : Totally, visual evoked potentials elicited by high contrast small checkerboard patterned stimuli were significantly reduced in amplitude and prolonged in latency in amblyopic eyes.

The mean intraocular amplitude difference was significantly larger in amblyopic than in normal groups.

There was also no difference between the healthy eye in the amblyopic group and the control one.

On binocular viewing, the amount of VEP amplitude was significantly greater in normal subjects than that in both amblyopic groups.

Regarding the type of amblyopia, the mean binocular VEP amplitude as compared to that in the non-amblyopic eye was greater for the anisotropic than the strabismus groups Conclusion: In both amblyopic groups, the VEP responses were significantly reduced in amplitude and prolonged in latency.

In binocular viewing, the amount of VEP amplitude was greater in normal subjects than both amblyopic groups.

The mean binocular amplitude was significantly greater for the anisotropic than for the strabismus group.