The role of immunohistochemistry in the diagnosis of mixed cellularity classical hodgkin lymphoma

الملخص EN

Immunohistochemistry has become a routine technique in the diagnosis of lymphoma in general, and Hodgkin lymphoma in particular, as well as in the differential diagnosis among different lymphoma subtypes and other malignant tumors.

Different immunomarkers have been applied to a lymph node sections .All were negative, except for CD30 which was positive in the malignant H/ RS cells , where as other markers were positive only in the reactive cells.

Nodular lymphocyte predominant Hodgkin lymphoma was excluded by negative CD20, LCA, EMA and anaplastic large cell lymphoma by negative EMA.