The effect of sodium chloride and cephalexin antibiotic on the growth of leishmania tropica and leishmania donovani promastigote

الملخص EN

T o examine the tested drugs (sodium chloride and Cephalexin), we tested the drugs in vitro against promastigote stage of parasite with multi concentrations of the drugs.

The viability of the parasite was counted daily to promastigote for 5 days.

Hypertonic sodium chloride solution LD 50 value against Leishmania donovani and Leishmania tropica promastigote was (0.021) and (0.04) mg/ml respectively, while Cephalexin LD 50 value against L.

donovani and L.

tropica promastigote was (1.4) and (2.55) mg/ml respectively.

Hypertonic sodium chloride solution and Cephalexin a wide-spectrum antibiotic have effective leishmaniacidal agents against L.

tropica and L.

donovani promastigote in vitro.