Activity and isoenzymes of alkaline phosphatase in patients with urinary schistosomiasis in Balad Rouz town, Diyala province

الملخص EN

A total of 1550 urine samples were collected from pupils and households in Balad Rouz town, Diyala province and examined for urinary schistosomiasis during the period from October 2005 till December 2006.

The total infection rate with Schistosoma haematobium was 2.13 %.

Serum and urine from all the 33 infected individuals and 25 controls were assayed for the estimation of alkaline phosphates (ALP) activity.

The study revealed a significant increase in ALP values in both serum and urine of infected individuals.

No significant differences in ALP activity were recorded among males and females and among different age groups.

Through polyacrylamide gel electrophoresis, ALP is enzymes revealed three banding patterns which differ from the three zymodems obtained from control group.

This is a cheap, reproducible and rapid method for detection of progressive disease in Schistosoma haematobium infection especially in endemic areas.