Lipid profile in children with beta-thalassemia major in Babylon

الملخص EN

The aim of the present study was to investigate the lipid pattern in children with beta thalassemia major in Babylon province.

Forty transfusion dependent beta – thalassemia major patient, 20 males and 20 Females (mean age 9±5 years) that undergo periodical blood transfusion and desferoxame as a chelating agent, were studied.

Twenty controls of matched age and gender were also included in this study.

Beta thalassemia major patients showed significantly lower total cholesterol, high density lipoprotein cholesterol, and low density lipoprotein cholesterol when compared with control.

Serum triglycerides levels of beta–thalassemia major patients were found to be significantly higher than levels in healthy children .

Results mentioned above revealed that lipid profile changed in patients with beta–thelassemia major.

Many factors such as iron over load, liver injury, hormonal disturbances and aging might cause these changes