Acute renal failure in falciparum malaria : clinical characteristics, demonstration of oxidative stress, and prognostication
المؤلفون المشاركون
Krishna, Ch. Venkata Rama
Rao, P. V. L. N. Srinivas
Kumar, V. Siva
Das, G. C.
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 23، العدد 2 (30 إبريل/نيسان 2012)، ص ص. 296-300، 5ص.
الناشر
تاريخ النشر
2012-04-30
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
In this prospective study, we aimed to assess the clinical characteristics of acute renal failure (ARF), determine oxidative stress, as well as to predict the outcome in patients with severe falciparum malaria (FM).
The study included a total of 75 subjects ; there were 25 adult patients with acute severe FM and ARF, 25 adult patients with uncomplicated FM without ARF, and 25 age-and sex-matched healthy subjects who served as controls.
In patients with severe FM and ARF (n = 25), renal failure was non-oliguric in 28% and oliguric in 72 %.
The average duration of renal failure was 10.53 ± 4.0 days.
Sixty percent recovered and 40 % died.
All patients with non-oliguric presentation recovered.
The mean serum malondialdehyde (MDA) levels were 0.82 ± 0.43 μmol / L, 2.97 ± 1.11 μmol / L, and 6.86 ± 2.62 μmol / L, respectively, in healthy controls, in patients with uncomplicated FM, and in those with severe FM with ARF.
The Acute Physiology Age and Chronic Health Evaluation II (APACHE II) score, Sequential Organ Failure Assessment (SOFA) score, and the Acute Tubular Necrosis-Individual Severity Index (ATN-ISI) score were all significantly higher in the expired group (19 ± 5.49) when compared to the survivor group (14.4 ± 3.15) (P = 0.014).
Kaplan–Meier survival analysis showed that survival was low in patients with delayed hospitalization and longer duration of symptoms.
Also, we observed a high occurrence of acute respiratory distress syndrome and central nervous system involvement among the patients who expired.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Krishna, Ch. Venkata Rama& Rao, P. V. L. N. Srinivas& Das, G. C.& Kumar, V. Siva. 2012. Acute renal failure in falciparum malaria : clinical characteristics, demonstration of oxidative stress, and prognostication. Saudi Journal of Kidney Diseases and Transplantation،Vol. 23, no. 2, pp.296-300.
https://search.emarefa.net/detail/BIM-292795
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Krishna, Ch. Venkata Rama…[et al.]. Acute renal failure in falciparum malaria : clinical characteristics, demonstration of oxidative stress, and prognostication. Saudi Journal of Kidney Diseases and Transplantation Vol. 23, no. 2 (Apr. 2012), pp.296-300.
https://search.emarefa.net/detail/BIM-292795
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Krishna, Ch. Venkata Rama& Rao, P. V. L. N. Srinivas& Das, G. C.& Kumar, V. Siva. Acute renal failure in falciparum malaria : clinical characteristics, demonstration of oxidative stress, and prognostication. Saudi Journal of Kidney Diseases and Transplantation. 2012. Vol. 23, no. 2, pp.296-300.
https://search.emarefa.net/detail/BIM-292795
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 299-300
رقم السجل
BIM-292795
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر