Primary hyperoxaluria type 1 in Tunisian children
المؤلفون المشاركون
Khalil, Nourchene
Yusuf, Gharbi
Karoui, Wiem
Abd al-Mawla, Juwaydah
Gargah, Tahar
Lakhoua, Muhammad Rashid
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 23، العدد 2 (30 إبريل/نيسان 2012)، ص ص. 385-390، 6ص.
الناشر
تاريخ النشر
2012-04-30
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
To determine the clinical, biological, and radiological futures of primary hyperoxaluria type 1 in Tunisian children, we retrospectively studied 44 children with primary hyperoxaluria type 1 who were treated in our center from 1995 to 2009.
The diagnosis was established by quantitative urinary oxalate excretion.
In patients with renal impairment, the diagnosis was made by infrared spectroscopy of stones or kidney biopsies.
The male-to-female ratio was 1 : 2.
The median age at diagnosis was 5.75 years.
About 43 % of the patients were diagnosed before the age of five years with initial symptoms dominated by uremia.
Four patients were asymptomatic and diagnosed by sibling screenings of known patients.
Nephrocalcinosis was present in all the patients; it was cortical in 34 %, medullary in 32 %, and global in 34 %.
At diagnosis, 12 (27 %) children were in end-stage renal disease.
Pyridoxine response, which is defined by a reduction in urine oxalate excretion of 60 % or more, was obtained in 27 % of the cases.
In the majority of patients, the clinical expression of primary hyperoxaluria type 1 was characterized by nephrocalcinosis, urolithiasis, and renal failure; pyridoxine sensitivity was associated with better outcome.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gargah, Tahar& Khalil, Nourchene& Yusuf, Gharbi& Karoui, Wiem& Lakhoua, Muhammad Rashid& Abd al-Mawla, Juwaydah. 2012. Primary hyperoxaluria type 1 in Tunisian children. Saudi Journal of Kidney Diseases and Transplantation،Vol. 23, no. 2, pp.385-390.
https://search.emarefa.net/detail/BIM-293000
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gargah, Tahar…[et al.]. Primary hyperoxaluria type 1 in Tunisian children. Saudi Journal of Kidney Diseases and Transplantation Vol. 23, no. 2 (Apr. 2012), pp.385-390.
https://search.emarefa.net/detail/BIM-293000
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gargah, Tahar& Khalil, Nourchene& Yusuf, Gharbi& Karoui, Wiem& Lakhoua, Muhammad Rashid& Abd al-Mawla, Juwaydah. Primary hyperoxaluria type 1 in Tunisian children. Saudi Journal of Kidney Diseases and Transplantation. 2012. Vol. 23, no. 2, pp.385-390.
https://search.emarefa.net/detail/BIM-293000
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 389-390
رقم السجل
BIM-293000
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر