![](/images/graphics-bg.png)
A dverse drug reactions of intermittent chemotherapy compared to daily regimen in Sudanese patients with pulmonary tuberculosis
المؤلفون المشاركون
Salih, Mutasim S. Muhammad
Muhyi al-Din, Hasan M.
al-Tayeb, Idris B.
Zaki, Abullahi M.
Idris, Badr al-Din Harun
Ahmad, Ala al-Din H.
المصدر
Sudan Journal of Medical Sciences
العدد
المجلد 7، العدد 2 (31 مارس/آذار 2012)، ص ص. 95-99، 5ص.
الناشر
جامعة أم درمان الإسلامية كلية الطب
تاريخ النشر
2012-03-31
دولة النشر
السودان
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Back ground: The World Health Organization (WHO) declared Tuberculosis a global health emergency in 1993 as it remains a major cause of mortality in developing countries.
The World Health Organization's Directly Observed Treatment Short course (DOTs) strategy achieve 87% success rate in the areas where it is implemented, usually with five drugs, lasts for 6months.
Till 1998 Sudan was classified as one of the slowly moving countries in implementation of the DOTS strategy and making no progress against tuberculosis.
Objective: A prospective comparative, randomized clinical trial, hospital based study carried out at Kosti Teaching Hospital using directly observed treatment short course (DOTS), to assess the adverse drug reactions of intermittent chemotherapy compared to the currently adopted short course therapy.
Methodology: Patients with smear positive new cases of tuberculosis were enrolled and randomized in to two groups, intermittent treatment group (A) and daily regimen group (B) .The raw data were introduced into SPSS program, the data comparison was carried out by Pearson Chi square and pair independent sample student T-test.
The level of significance (P<0.05).
Results: A total of 275 were studied, significant initial (pre-interventional) elevated means of aspartate aminotransferase (AST) was detected in the two groups and significantly in the intermittent regimen after two and four months, but the decrease was significant only after two months in the daily group.
Conclusion: Liver injury following antituberculous treatment was minimal and the adverse drug reactions were tolerable concerning the majority of the patients completing the course of the treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salih, Mutasim S. Muhammad& al-Tayeb, Idris B.& Zaki, Abullahi M.& Idris, Badr al-Din Harun& Ahmad, Ala al-Din H.& Muhyi al-Din, Hasan M.. 2012. A dverse drug reactions of intermittent chemotherapy compared to daily regimen in Sudanese patients with pulmonary tuberculosis. Sudan Journal of Medical Sciences،Vol. 7, no. 2, pp.95-99.
https://search.emarefa.net/detail/BIM-301025
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salih, Mutasim S. Muhammad…[et al.]. A dverse drug reactions of intermittent chemotherapy compared to daily regimen in Sudanese patients with pulmonary tuberculosis. Sudan Journal of Medical Sciences Vol. 7, no. 2 (Jun. 2012), pp.95-99.
https://search.emarefa.net/detail/BIM-301025
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salih, Mutasim S. Muhammad& al-Tayeb, Idris B.& Zaki, Abullahi M.& Idris, Badr al-Din Harun& Ahmad, Ala al-Din H.& Muhyi al-Din, Hasan M.. A dverse drug reactions of intermittent chemotherapy compared to daily regimen in Sudanese patients with pulmonary tuberculosis. Sudan Journal of Medical Sciences. 2012. Vol. 7, no. 2, pp.95-99.
https://search.emarefa.net/detail/BIM-301025
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 98-99
رقم السجل
BIM-301025
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)