Comparison of 8 Gy single fraction versus 20 Gy in five fractions or 30 Gy in 10 fractions radiotherapy for the treatment of metastatic bone pain
المؤلفون المشاركون
al-Hawwari, Bilal
Tilfah, Ahmad M.
المصدر
Journal of the Royal Medical Services
العدد
المجلد 19، العدد 2 (30 يونيو/حزيران 2012)، ص ص. 36-43، 8ص.
الناشر
الخدمات الطبية الملكية الأردنية
تاريخ النشر
2012-06-30
دولة النشر
الأردن
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
-Objectives: The aim of this study was to compare the effectiveness of pain control of most common fractionation used in oncology to treat bone metastases which are 8Gy single fraction, 20Gy in five fractions and 30Gy in 10 fractions.
Method: A total sample of 120 patients who were known to have stage IV cancer with bone metastasis were allocated to receive either 8Gy single fraction, 20Gy in five fractions or 30Gy in 10 fractions for the treatment of their pain between January 2007 and December 2009 at King Hussein Medical Center.
Pain severity and analgesic requirements were recorded by the investigator on a questionnaire before treatment, at two weeks and at one, two, three, four, five, six, eight, 10 and 12 months after radiotherapy.
Pain relief was the primary endpoint of treatment benefit.
Results: There was no difference in the time to first improvement in pain, time to complete pain relief, or in time to first increase in pain at any time up to 12 months after randomization, nor in the class of analgesics used.
Retreatment was twice as common after 8Gy as after multifraction radiotherapy, although retreatment for residual or recurrent pain did not reflect a difference between the three groups in the probability of pain relief.
Conclusion: A single fraction of 8Gy when used for the treatment of bone metastasis is as safe and effective as a multifraction regimen for the palliation of metastatic bone pain for at least 12 months.
This may make it suitable alternative to the multifraction radiotherapy regimens.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Hawwari, Bilal& Tilfah, Ahmad M.. 2012. Comparison of 8 Gy single fraction versus 20 Gy in five fractions or 30 Gy in 10 fractions radiotherapy for the treatment of metastatic bone pain. Journal of the Royal Medical Services،Vol. 19, no. 2, pp.36-43.
https://search.emarefa.net/detail/BIM-308863
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Hawwari, Bilal& Tilfah, Ahmad M.. Comparison of 8 Gy single fraction versus 20 Gy in five fractions or 30 Gy in 10 fractions radiotherapy for the treatment of metastatic bone pain. Journal of the Royal Medical Services Vol. 19, no. 2 (Jun. 2012), pp.36-43.
https://search.emarefa.net/detail/BIM-308863
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Hawwari, Bilal& Tilfah, Ahmad M.. Comparison of 8 Gy single fraction versus 20 Gy in five fractions or 30 Gy in 10 fractions radiotherapy for the treatment of metastatic bone pain. Journal of the Royal Medical Services. 2012. Vol. 19, no. 2, pp.36-43.
https://search.emarefa.net/detail/BIM-308863
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 42-43
رقم السجل
BIM-308863
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر