Study of some hematological and biochemical parameters in patients with untreated breast cancer in Erbil City

العناوين الأخرى

دراسة بعض العوامل الدموية و الكيميوحيوية في المريضات بسرطان الثدي قبل المعالجة في مدينة أرابيل

مقدم أطروحة جامعية

Shaykhah, Gawhar Ahmad

مشرف أطروحة جامعية

Mawlud, Kulthum Assaf

أعضاء اللجنة

Mahmud, Sadi Muhammad
Aziz, Jamal Muhammad
Amin, Kamaran Y. Muhammad

الجامعة

جامعة صلاح الدين

الكلية

كلية العلوم

القسم الأكاديمي

قسم علم الأحياء

دولة الجامعة

العراق

الدرجة العلمية

ماجستير

تاريخ الدرجة العلمية

2012

الملخص الإنجليزي

This study was carried out in Rizgary and Hawler teaching hospital in Erbil city from the period of August 2010 to June 2011.

A total of 115 patients with breast mass (55 malignant and 60 benign) and 40 women selected as control group participated.

In this study some hematological and biochemical parameters were determined in patients and control group.

The results show obviously relation between risk factor and breast cancer.

among these factors are : 1.

Age revealed that the most frequent ages for breast cancer are that at age group (38-47) compared with other groups.

2.

Higher frequency of breast cancer was found in married patient compared with singles and widows.

3.

Percentage of patients starting age menarche after 12 year was higher when compared with patients starting at or before 12 year.

4.

Number of patients with body mass index (BMI > 25kg / m2) was higher compared with number of patients having BMI < 20.

5.

The results show that the percentage of patients get married after 18 years and more was higher compared with patients married before 18 years.

6.

First pregnancy at age 20 years and over was found to be higher than other groups.

7.

Patients with breast cancer whom used oral contraceptive pill have higher percentage compared with benign breast disease patients.

8.

Percentage of patient's breast cancer and benign breast disease which diagnosed premenopausal was higher than postmenopausal.

9.

The number of patients diagnosed as third stage and fourth was higher compared with the number of patients diagnosed as second stage, unknown and first stage.

According to the type of benign breast disease, the unknown cause showed higher percentage compared with other type.

10.

Patients which not used hormone replacement therapies (HRT) have higher percentage compared with patients used HRT.

11.

Higher percentage recorded in breast cancer and benign breast disease patients with none educational level.

12.

According to hematological parameter the higher mean frequency was found in (48-57) age intervals compared with other intervals while the lowest mean was found in (38-47) and (18-27) age intervals, and most of these parameters increased significantly in malignant and benign group compared with control group.

13.

Higher level of liver enzyme Alanine transaminases, Aspartae transaminase, Alkaline phosphatase was found age intervals (18-27),(38-57) and 58 and older respectively.

While the lowest level of Aspartae transaminase, Alkaline phosphatase was found in (18-27) and the lowest mean of Alanine transaminases was in 58 and older age interval 14.

Higher frequency of lipid profile test was found in (48-57) age intervals, with lowest level in (18-27) age intervals 15.

Body mass index recorded higher mean level in 58 and older with lower level in 18-27age intervals with non-significant increase in malignant and benign group compared with control group.

16.

Highest mean level of total protein, ferritin and tumor marker was found in (75-48), (47-38) and (18-27) age intervals and lowest level was found in (38-47), (18-27) and (48-57) age intervals respectively, with significant increase in total protein and tumor marker in malignant and benign group compared with control group.

17.

Twenty patients showed a positive serum soluble human epidermal growth factor receptor with significant increase in mean concentration compared with control group.

التخصصات الرئيسية

الأحياء

الموضوعات

• السرطان(مرض)
• العراق
• أربيل
• الثدي
• علم الدم

عدد الصفحات

94

قائمة المحتويات

• APA
• MLA
• AMA

لغة النص

الإنجليزية

نوع البيانات

رسائل جامعية

رقم السجل

BIM-314408