The role of spirulina platensis (Arthrospira platensis)‎ in growth, Immunity, P53 level of nile tilapia (Oreochromis niloticus)‎ and its resistance to infection

الملخص EN

The current study was designed to optimize the dietary levels of Spirulina platensis in Oreochromis niloticus; this was tested via graded levels.

Six is nitrogenous and is caloric rations containing graded levels of dried spirulina 0, 5, 7.5, 10, 15 and 20g / kg diet were fed separately to six equal groups of O.

niloticus fingerlings for 3 months.

Growth performance, non-specific immune parameters, tissue reactions and resistance of tilapias post challenge infection with Pseudomonas fluorescens were estimated monthly.

There were a significant increase in growth performance parameters and survival rates in spirulina-supplemented groups at the concentration level of 10 g / kg for 2 months.

Significant increases in hematocrit, nitroblue tetrazolium and lysozyme activity were observed in most of the supplemented groups.

The expression level of P53 showed a declination among the treated groups in time and dose dependent manner.

Bacterial challenge infections resulted in a significantly lower mortality rates in all Spirulina groups with a remarkable increase in protection of fish received 10 g / kg.

In sum, it is advisable to incorporate 10 g / kg diet of spirulina for 2 months for maximum growth performance, immunity and disease resistance in O.

niloticus