The detection of silent celiac disease in patients with type 1 diabetes mellitus by the use of anti tissue transglutaminase antibodies
المؤلفون المشاركون
Kubba, Rushdi A. H.
Ubayd, Anwar Tuma
al-Hirjani, Zaydan K.
المصدر
al-Kindy College Medical Journal
العدد
المجلد 8، العدد 1 (30 يونيو/حزيران 2012)، ص ص. 131-135، 5ص.
الناشر
تاريخ النشر
2012-06-30
دولة النشر
العراق
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective: Detection the presumptive prevalence of silent celiac disease in patients with type 1 diabetes mellitus with determination of which gender more likely to be affected.
Methods: One hundred twenty asymptomatic patients [75 male , 45 female] with type 1 diabetes mellitus with mean age ± SD of 11.25 ± 2.85 year where included in the study .
All subjects were serologically screened for the presence of anti-tissue transglutaminase IgA antibodies (anti-tTG antibodies) by Enzyme- Linked Immunosorbent Assay (ELISA) & total IgA was also measured for all using radial immunodiffusion plate .
Anti-tissue transglutaminase IgG was selectively done for patients who were expressing negative anti-tissue transglutaminase IgA with low total IgA levels & results were compared to that obtained from healthy 60 persons with mean age ± SD for them was 15.25 ± 3.85 year .
Results : Fourteen out of one hundred twenty (11.66 % ) diabetic patients had expressed positivity to antitissue transglutaminase IgA compared to 1/60 ( 1.66 %) of non diabetic patients who had expressed such positivity , P value equals to 0.0221 & it is considered to be statistically significant.
Three out of one hundred twenty (2.5 % ) diabetic patients had expressed total IgA deficiency whereas all of non diabetic patients were expressing total IgA within the normal range , P value equals to 0.55 & it is considered to be not statistically significant.
All of three diabetic patients with total IgA deficiency were not showing positivity to anti-tissue transglutaminase IgG .
Six mals & Eight female of those with type 1 diabetes mellitus had expressed positivity to anti-tissue transglutaminase IgA , P value equals to 0.1426 & it is considered to be not statistically significant .
Conclusion : There is an increased prevalence of IgA antitissue transglutaminase antibodies ( 11.66 % ) in children & adolescent with type 1 diabetes mellitus in comparison with control group.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ubayd, Anwar Tuma& Kubba, Rushdi A. H.& al-Hirjani, Zaydan K.. 2012. The detection of silent celiac disease in patients with type 1 diabetes mellitus by the use of anti tissue transglutaminase antibodies. al-Kindy College Medical Journal،Vol. 8, no. 1, pp.131-135.
https://search.emarefa.net/detail/BIM-316970
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kubba, Rushdi A. H.…[et al.]. The detection of silent celiac disease in patients with type 1 diabetes mellitus by the use of anti tissue transglutaminase antibodies. al-Kindy College Medical Journal Vol. 8, no. 1 (Jun. 2012), pp.131-135.
https://search.emarefa.net/detail/BIM-316970
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ubayd, Anwar Tuma& Kubba, Rushdi A. H.& al-Hirjani, Zaydan K.. The detection of silent celiac disease in patients with type 1 diabetes mellitus by the use of anti tissue transglutaminase antibodies. al-Kindy College Medical Journal. 2012. Vol. 8, no. 1, pp.131-135.
https://search.emarefa.net/detail/BIM-316970
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 134-135
رقم السجل
BIM-316970
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر