Effect of liqurice and chamomile extracts in the management of gastric ulcer in rats

الملخص EN

Back ground : gastric hyperacidity and peptic ulcer are very common causes of human suffering.

Although there are different types of antiulcer drugs still they are expensive and have many side effects.

Objective: To investigate the antiulcer activity of watery extracts of (liqurice and chamomile) and chamomile oil in rats models.

Material and methods : Liqurice (glycyrrhiza glabra) roots extraction by crushing and boiling, while chamomile extraction by hot water maceration and the yield were used after cooling.

Antiulcer effects were evaluated in rats using ethanol and salicylic acid ulcer induced method.

Results : the aqueous extract of chamomile and liqurice and chamomile oil exhibited significant (p < 0.05) anti-ulcer activity in this ulcer induced models compared with omeprazole as standard drug.

Discussion : the protection effects of these plants extracts may be due to its antioxidant contain and protective effect on the lining mucosa by enhancing the protection factors.