Epoxidationof ferutinin by different fungi and antibacterial activity of its metabolite

الملخص EN

Structural transformation of the sesquiterpene ester, ferutinin (1), by suspended fungal cultures of Aspergillus Niger, Rhizopus stolonifer, and Fusarium lini, resulted in the formation of a metabolite.

This metabolite was identified as ferutinin α-epoxide (2), by different spectroscopic techniques.

Metabolite 2 showed a good antibacterial activity against Staphylococcus aureuscompared to ferutinin (1).