Immunohistochemical study of PDGF, IGF of radiated tooth rat embryo
المؤلفون المشاركون
al-Hijazi, Adhra Yahya
Salih, Rasim Mahdi
المصدر
Journal of Baghdad College of Dentistry
العدد
المجلد 25، العدد 1 (31 مارس/آذار 2013)، ص ص. 110-115، 6ص.
الناشر
تاريخ النشر
2013-03-31
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background : Exposure to microwaves radiation from microwave oven may be harmful for users especially for the one who have highest contact with microwave oven.
Because the body is electrochemical in nature, any force that disrupts or changes human electrochemical events will affect the physiology of the body by destabilization and interruption of many chemical body substance including growth factors.
The insulin-like growth factors (IGFs) are a family of mitogenic proteins that control growth, differentiation, and the maintenance of differentiated function in numerous tissues.
It fulfils an important role in growth and development of teeth, mandible, maxillae, and tongue.
Platelet derived growth factors (PDGF) are proteins that regulate cell growth and division.
In particular, it plays a significant role in blood vessel formation (angiogenesis).
It seems that IGF and PDGF share in much tissue developmental process.
Therefore they included in the present study in correlation to tooth growth and development.
This study Illustrates the expression of insulin like growth factor and platelet derived growth factor by dental cells of rat embryos at periods of gestation 16th,18thday intrauterine life(I.
U.
L) and one day neonatal life. Materials and Methods : Animal model: Thirty-six female rats were used in this study.
Starting from zero days (time of gestation that recorded) the pregnant rats were divided into three groups.
Group A serve as a control, groups B exposed to microwave oven radiation For (15 / minutes ; 5 / min / hour for 3 hours continuously) daily and C exposed to EMF radiation for (45 minutes ;15 min /hour for3hours continuously)daily starting from zero day of gestation till the last day.
The embryo of rats at 16thday and 18th day of intrauterine life and one day old rat (new born rat) were studied immunohistochemically for localized of platelet derived growth factor (PDGF) and insulin growth factor (IGF) markers. Results :The results showed that experimental group (B) exposed to short duration of radiation (5 / min.) stimulates the development of tooth germ and faster tooth growing in comparison to control with immunohistochemical results show strong to moderate intense stain for positive expression of growth factors(PDGF,IGF) by dental tissue.For long exposure period of radiation( group C) , it showed retardation in the tooth growth withimmunohistochemical findings record weak to negative intense stain for the expression of growth factors(PDGF, IGF) by dental tissue. Conclusion : Exposure to microwave (oven) radiation during pregnancy may play a role in the expression of IGF and PDGF by cells of tooth germ thatinfluence on cell differentiation and physiological activity of specialized dental cells, depending on exposure time.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salih, Rasim Mahdi& al-Hijazi, Adhra Yahya. 2013. Immunohistochemical study of PDGF, IGF of radiated tooth rat embryo. Journal of Baghdad College of Dentistry،Vol. 25, no. 1, pp.110-115.
https://search.emarefa.net/detail/BIM-324074
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salih, Rasim Mahdi& al-Hijazi, Adhra Yahya. Immunohistochemical study of PDGF, IGF of radiated tooth rat embryo. Journal of Baghdad College of Dentistry Vol. 25, no. 1 (Mar. 2013), pp.110-115.
https://search.emarefa.net/detail/BIM-324074
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salih, Rasim Mahdi& al-Hijazi, Adhra Yahya. Immunohistochemical study of PDGF, IGF of radiated tooth rat embryo. Journal of Baghdad College of Dentistry. 2013. Vol. 25, no. 1, pp.110-115.
https://search.emarefa.net/detail/BIM-324074
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 115
رقم السجل
BIM-324074
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر