Antibacterial activity of the solasodine of solanum nigrum against bacterial isolates from the wounds

الملخص EN

In this study, 80 clinical samples collected from patients including wound, blood, urine and cerebrospinal fluid and isolates of Gram-positive and Gram-negative bacteria were identified.

The inhibitory effects of ethyl alcohol extracts and solasodine compound of Solanum nigrum were tested on clinical isolates of the wound included: Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa.

The ethyl alcohol extract showed inhibitory activity on all tested bacterial Spp.

All the activities were compared with a tetracycline.

The Minimum Inhibitory Concentration (MIC) of the Solasodine were 8, 6, 4, 8 mg / ml respectively for S.

aureus, S.

epidermidis, E.

coli and P.

aeruginosa respectively .The results lend scientific credence to justify the use of the Solasodine compound against bacterial isolates of the wounds and some bacterial diseases.